Molecular Mechanisms of Drug Resistance and Metastasis
Dr. Sahin gave a talk entitled “From mechanisms of drug resistance to drug discovery” at the 8th Multidisciplinary Cancer Research Congress held by Istinye University, Istanbul – January 16, 2021. The talk was well received by the audience with multiple Read More …
Our project aiming at overcoming chemotherapy resistance in TNBC via targeting lysyl oxidase (LOX) was chosen for presentation at National NIGMS IDeA Program Virtual Meeting – September 22, 2020. Our discovery of this novel drug resistance mechanism was recently published Read More …
Our latest article has been published in Nature Communications. The study focuses on the identification of lysyl oxidase (LOX) protein as a major chemotherapy resistance modulator in triple negative breast cancer. We showed that targeting LOX overcomes chemoresistance in TNBC. Read More …
Dr. Sahin received the prestigious American Cancer Society Research Scholar Grant. The grant, totaling nearly $800,000 over the next four years, will support our research on overcoming tamoxifen resistance and blocking metastasis in breast cancer. Our hope is that the Read More …