Our latest article has been published in Cell Death & Differentiation. The study focuses on the molecular mechanism of Transforming Acidic Coiled-Coil Containing Protein 3 (TACC3) in highly aggressive breast tumors with Centrosome amplification (CA). We demonstrated, for the first time, that TACC3 forms distinct functional interactomes regulating different processes in mitosis and interphase to ensure proliferation and survival of cancer cells with CA.

Read the article here.


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