Our latest article has been published in Cell Death & Differentiation. The study focuses on the molecular mechanism of Transforming Acidic Coiled-Coil Containing Protein 3 (TACC3) in highly aggressive breast tumors with Centrosome amplification (CA). We demonstrated, for the first time, that TACC3 forms distinct functional interactomes regulating different processes in mitosis and interphase to ensure proliferation and survival of cancer cells with CA.
Read the article here.
“Hollings team marks milestone in progress toward investigational new drug for triple-negative breast cancer” https://hollingscancercenter.musc.edu/news/archive/2024/07/22/lox-inhibitor-for-triple-negative-breast-cancer
A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer https://www.sciencedirect.com/science/article/pii/S2451945624002733?via%3Dihub
We participated in the AACR conference with three distinct poster presentations.
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