OZGUR SAHIN LAB – Page 4 – Molecular Mechanisms of Drug Resistance and Metastasis

Dr. Sahin presents our project on targeting LOX in TNBC at the National NIGMS IDeA PI Meeting

Our project aiming at overcoming chemotherapy resistance in TNBC via targeting lysyl oxidase (LOX) was chosen for presentation at National NIGMS IDeA Program Virtual Meeting – September 22, 2020. Our discovery of this novel drug resistance mechanism was recently published in one of the most selective and prestigious scientific journals (Nature Communications). We are hopeful that our findings will pave the way to develop novel drugs targeting LOX for the treatment of TNBC that do Read more…

By sahinozgur, 5 yearsSeptember 22, 2020 ago

Publication

Our new paper is published in Nature Communications

Our latest article has been published in Nature Communications. The study focuses on the identification of lysyl oxidase (LOX) protein as a major chemotherapy resistance modulator in triple negative breast cancer. We showed that targeting LOX overcomes chemoresistance in TNBC. Read the article here.

By sahinozgur, 5 yearsMay 15, 2020 ago

Announcement

Dr. Sahin receives the prestigious American Cancer Society Research Scholar Grant (ACS-RSG)

Dr. Sahin received the prestigious American Cancer Society Research Scholar Grant. The grant, totaling nearly $800,000 over the next four years, will support our research on overcoming tamoxifen resistance and blocking metastasis in breast cancer. Our hope is that the research results from this grant will lay the foundation for repositioning available drugs that will prevent patients from becoming resistant to their treatments. Please read more at here.

By sahinozgur, 6 yearsJanuary 1, 2020 ago